More and complete info on CIALIS

Posted by Pharmaceutical-Stuff on Saturday 23 February 2008

Generic Name: (tah DAL a fil)
Brand Names:

What is ?
relaxes muscles and increases to particular areas of the body. is used to treat (). may also be used for purposes other than those listed in this medication guide.

Before taking
Do not take if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket). Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite (”poppers”). Taking with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack.

Before taking , tell your doctor if you are allergic to any drugs, or if you have:

  •       heart disease or heart rhythm problems;
  •       a recent history a heart attack (within the past 90 days);
  •       a recent history of stroke or congestive heart failure (within the past 6 months);
  •       angina (chest pain);
  •       high or low blood pressure;
  •       liver disease;
  •       kidney disease (or if you are on dialysis);
  •       a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
  •       a bleeding disorder such as hemophilia;
  •       a stomach ulcer;
  •       retinitis pigmentosa (an inherited condition of the eye);
  •       a physical deformity of the (such as Peyronie’s disease); or
  •       if you have been told you should not have sexual intercourse for health reasons.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take .

This medication can decrease to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking , most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. It is not clear whether is the actual cause of vision loss. Stop using and get emergency medical help if you have sudden vision loss.

FDA pregnancy category B: Although is not for use in women, this medication is not expected to be harmful to an unborn baby. Do not use without telling your doctor if you are pregnant or plan to become pregnant during . Although is not for use in women, it is not known if passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. You may need a lower dose of this medication if you are older than 65. Follow your doctor’s instructions.

What happens if I miss a dose?
Since is used as needed, you are not likely to be on a dosing schedule.

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.
What should I avoid while taking ?
Avoid drinking alcohol, which can increase some of the of .

Grapefruit and grapefruit juice may interact with . Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Avoid using other medicines to treat , such as alprostadil (Caverject, Muse, Edex) or yohimbine (Yocon, Yodoxin, others), without first talking to your doctor.

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About Cialis

Posted by Pharmaceutical-Stuff on Saturday 23 February 2008

How works:
When an goes limp, you have PDE5 to thank. Specialized tissue produces a substance called cyclic guanosine monophosphate (cGMP) in response to sexual stimulation. The more cGMP available, the more durable the . inhibits the PDE5 enzyme, preserving cGMP levels, therefore aiding viability and durability.

About Cialis

  • was developed by , a relatively small biotech company located in Washington State, in the United states. has formed a 50/50 joint venture with American Pharmaceutical Giant, Eli Lilly & company. The partnership is called Lilly .
  • is known as the ” 36 hour pill” or the “weekend pill” because unlike other similar drugs, has a long duration of action.
  • received approval for use in the United States November 21, 2003.
  • is a member of a family of drugs known as PDE5 enzyme inhibitors.
  • is a member of a family of drugs called PDE5 Inhibitors. is now marketed in approximately 40 countries and is available by prescription in pharmacies on five continents.
  • blocks an enzyme that causes an to go flaccid. Although is similar to and , its dose, onset of action, and duration of action is unique.

Some very smart scientists discovered that cyclic guanosine monophosphate (cGMP) was the key to sustaining an . They discovered that when a man gets stimulated, a chain reaction occurs in the tissue of the that in elevated levels of a substance called cyclic guanosine monophosphate (cGMP). As long as there are sufficient levels of cGMP, the can remain erect. The more cGMP, the more robust and durable the . If you inhibit the degradation of cGMP it stays around in the longer, producing a more durable . Another way you can think of (and all other similar medicines) is that it preserves the elevated levels of cGMP that are created when a man is stimulated for a stronger, more lasting .

That’s how works - blocks the enzyme phosphodiesterase-5 (PDE5) which is responsible for the neutralization of cGMP. () is a highly selective inhibitor of PDE5. (PDE5 is not the only phosphodiesterase involved in the physiology but it appears to be the most important one). The nice thing about PDE5 blockers is that they shouldn’t cause erections at inappropriate times because they only block degradation of cGMP produced in reaction to sexual stimulation, such as thinking about something sexy. If you are not being stimulated, there is no cGMP to protect, so the drug remains in the background.

Dose:
is available 10mg and 20mg tablets. The recommended dose is 10mg taken prior to anticipated sexual activity and without regard to food. In those patients in whom 10mg does not produce an adequate effect, 20mg might be tried. It can be taken from 30 minutes to 12 hours prior to sexual activity. The efficacy of may persist up to 24 hours post-dose.
The maximum recommended dose is one pill per day.

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Viagra the treatment for Erectile Dysfunction

Posted by Pharmaceutical-Stuff on Friday 22 February 2008

needs no introduction! Pfizer’s wonder drug, sildenafil, better known as , is the trusted for male problems. Introduced in 1998, , the famous (ED) drug, has been a profound influence in the human souls by such a fathom that not a single day has passed without seeing ads of the magical pill.

Viagra the treatment for Erectile Dysfunction

(ED), also known as , is the inertia of sustaining an erect , during or before sexual intercourse. () - inability to maintain the of the for satisfactory sexual intercourse in spite of the capability of .

has been a proved veteran in the of (), which acts by increasing to the , thus improving a man’s response to sexual stimulation, thus allowing him to lead a normal sexual life. With in your hand, you are no longer an alien in solitude and signifying the dusk of unsung glory.

Viagra the treatment for Erectile Dysfunction

works by helping the blood vessels in the to relax, allowing blood to flow into the causing an . For to be effective, sexual stimulation is required.

comes to your rescue: Sex is a priority, for the matured ones, when followed with the “Maslow’s Law of Hierarchy”, so try to avert any kind of shyness when it comes to bestow manhood.

Viagra the treatment for Erectile Dysfunction

Cures (VC) is your compendium - a comprehensive information portal on , , success stories, latest news and even humor related to and all other related issues. Special features include Message Forum which is an effort towards building an online community to share, discuss, and ask problems or new information on and .

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